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 Chun-Che, Lin

 TEL:04-24730022#11017
 EMAIL:forest65@csmu.edu.tw
 OFFICE:正心樓13樓校長室

Present Position :

Vice President, Chung Shan Medical University (2023.8 ~ )

Professor, School of Medicine, Chung Shan Medical University (2012. 2~ )

Leadership Experience :

1. Dean, College of Medicine, Chung Shan Medical University(2014. 8~2017.7 )

2. Vice Superintendent, Medical Education Department, CSMUH (2014. 8~2017.7)

3. Director, Program of Postgraduate Medical Training, CSMUH (2006.8~2017.7 )

4. Director, Department of Internal Medicine, CSMUH (2011-2014)

5. Vice superintendent, Center for Digestive Medicine, CMUH (2019. 8~2022.7)

6. Director, Center of Health Evaluation and Promotion CMUH (2020. 7~2022.7)

Education :

1. Bachelor of Medicine, Chung Shan Medical University (1990)

2. Ph.D. ,Institute of Medicine, Chung Shan Medical University (2005)

Professional Training and Appointment :

1999-2019 Attending Physician, Division of Gastroenterology and Hepatology,

Chung Shan Medical University Hospital

1997-1999 Attending Physician, EnChuKongHospital

1995-1997 Fellow, Division of Gastroenterology and Hepatology,

Department of Internal Medicine, NTUH

1992-1995 Resident, Department of Internal Medicine, NTUH

1990-1992 Second Lieutenant, Military Service

1989-1990 Intern, National Taiwan University Hospital

Personal Speciality :

Internal Medicine, Gastroenterology,Hepatology, Ultrasonography,Endoscopy, Medical Education

Publications :

1. Lin CC, Wang HP, Wu MS, Wang TH, Lin JT. Incomplete Pancreas Divisum Coexistent with Anomalous Union of Pancreaticobiliary Duct - Report of A Chinese Patient. Hepato-Gastroenterology 1996; 43: 1650-1652. (SCI)

2. Lin CC, Wang HP, Lin JT, et al. Chronic Calcifying Pancreatitis In Taiwan: Multicentric Study and Comparison with Western Countries. Hepato-Gastroenterology. 1997; 44: 842-848. (SCI)

3. Wu MS, Wang HP, Lin CC, Lin JT, et al. Loss of imprinting and overexpression of IGF2 gene in gastric adenocarcinoma. Cancer Letters 1997; 120: 9-14. (SCI)

4. Wu MS, Yang KC, Lin CC, Wang HP, Lin JT, et al. Distinct Clinicopathologic Characteristics of Diffuse and Intestinal Type Gastric Cancer in Taiwan. Journal of Clinical Gastroenterology. 1997; 25: 646-649(SCI)

5. Chen JH, Wang HP , Wu MS, Chou AL, Lin CC, Lin JT, et al. Gastric Leiomyosarcoma Mimicking a Cyst Tumor at the Pancreatic Tail - One Case Report. Hepato-Gastroenterology. 1998; 45(24):2468-2470, (SCI)

6. Lin CC, Wang HP, Lin JT, et al. Pancreas Divisum Coexistent with Gallbladder Carcinoma - Report of A Chinese Patient Hepato-Gastroenterology, 1998; 45, 879-881. (SCI)

7. Chang LY, Wang HP, Wu MS, Wang HH, Lin CC, Lin JT. Anomalous Pancreaticobiliary ductal union - an etiologic association of gallbladder cancer and adenomyomatosis. Hepato-Gastroenterology. 1998; 45(24) :2016-2019 (SCI)

8. Wang HP, Wu MS, Lin CC, Chang LY, Kao AW, Wang HH, Lin JT. Pancreaticobiliary Disease Associated with Anomalous Pancreaticobiliary Ductal Union. Gastrointestinal Endoscopy 1998; 48: 184-189. (SCI)

9. Chen JH, Wang HP, Wu MS, Chou AL, Lin CC, Lin JT, et al. Gastric Leiomyosarcoma Mimicking a Cyst Tumor at the Pancreatic Tail One Case Report. Hepato- Gastroenterology,1998; 45(24):2468-70, (SCI)

10. Wang HH. Wu MS. Shun CT. Wang HP. Lin CC. Lin JT. Lymphoepithelioma-like carcinoma of the stomach: a subset of gastric carcinoma with distinct clinic pathological features and high prevalence of Epstein-Barr virus infection. Hepato-Gastroenterology.1999; 46(26):1214-1219 (SCI)

11. Lin CC, Chen TH, Ho WC, Chen TY. Endoscopic treatment of a Cameron lesion presenting as life-threatening gastrointestinal hemorrhage. Journal of Clinical Gastroenterology 2001; 33: 423-424 (SCI)

12. Wang HP, Huang SP. Sun MS, Chen JH, Wang HH, Lin CC, Chang YS, Yang CS, Wu MS, Lin JT. Urgent endoscopic nasobiliary drainage without fluoroscopic guidance: A useful treatment for critically ill patients with biliary obstruction. Gastrointestinal Endoscopy. 2001; 52(6):741-744 (SCI)

13. Lin CC, Ho WC, Chen TH, Chang SW, Chen TY. Pneumoperitoneum, pneumomediastinum and subcutaneous emphysema in a patient with pyloric stenosis after endoscopic balloon dilatation-report of a case. Gastroenterological Journal of Taiwan. 2002; 19: 205-209.

14. Huang SP, Wang HP, Lee YC, Lin CC, Yang CS, Wu MS, Lin JT. Endoscopic hemoclip placement and epinephrine injection for Mallory-Weiss syndrome with bleeding. Gastrointestinal Endoscopy. 2002; 55: 842-846 (SCI)

15. Lee YC. Wang HP. Yang CS. Yang TH. Chen JH. Lin CC. Tsai CY. Chang LY. Huang SP. Wu MS. Lin JT. Endoscopic hemostasis of a bleeding marginal ulcer: hemoclipping or dual therapy with epinephrine injection and heater probe thermocoagulation. Journal of Gastroenterology & Hepatology. 17(11):1220-1225, 2002 Nov. (SCI)

16. Chang MC, Su CH, Sun MS, Huang SC, Chiu CT, Chen MC, Lee KT, Lin CC, Lin JT.Etiology of acute pancreatitis--a multi-center study in Taiwan. Hepato-Gastroenterology. 50(53):1655-1657, 2003 Sep-Oct (SCI)

17. Chen TY, Chen TH, Ho WC, Lin CC, Lin CK, Ho LC. A clinical study on pyogenic liver abscess. Chung Shan Medical Journal. 2003; 14: 495-503.

18. Ho WC, Lin CC, Lin CP, Lin CK, Chen TH, Chen TY. Percutaneous endoscopic gastrostomy (PEG): three years clinical experience in CSMUH. Chung Shan Medical Journal. 2004; 15: 149-152.

19. Lin CC, Yin MC, Hsu CC, and Lin MP. Effect of Five Cysteine-Containing Compounds on Three Lipogenic Enzymes in Balb/cA Mice Consuming High Saturated Fat Diet. Lipids. 2004; 39: 843-848. (SCI)

20. Lin CC, Ho WC, Chen TH, Chen TY, Lin CK. The need for urgent colonoscopy for critically ill patients with acute lower gastrointestinal bleeding. Chung Shan Medical Journal. 2005; 16: 261-271 (non-SCI)

21. Lin CC, Lee YC, Lin JT, Lee H, Ho WC, Wang HP. Bedside colonoscopy for critically ill patients with acute lower gastrointestinal bleeding. Intensive Care Medicine 2005; 31: 743-746.(SCI)

22. Hsu CC, Lin CC Liao TS, Yin MC. Protective effect of s-allyl cysteine and s-propyl cysteine on acetaminophen-induced hepatotoxicity in mice. Food and Chemical Toxicology. 2006;44:393-397.(SCI)

23. Chen TH, Chen TY, Hsu LY, Lin CK, Lin CC. Hookworn infestation diagnosed by capsule endoscopy. Gastrointestinal Endoscopy. 2006; 64:277-278. (SCI) (correspondence author).

24. Lin CC, Wang HP, Wu MS, Ho WC, Lee H, Lin JT. The etilology and clinical characteristics of acute lower gastrointestinal bleeding in patients hospitalized for comorbid illnesses. Hepato-Gastroenterology. 53:391-394, 2006 May-June (SCI)

25. Lin CC, Yin MC. B vitamins deficiency and decreased anti-oxidative state in patients with liver cancer. European Journal of Nutrition. 2007; 46: 293-299 (SCI)

26. Lin CC, Yin MC, Liu WH. Alleviative effects of s-allyl cysteine and s-ethyl cysteine on MCD diet-induced hepatotoxicity in mice. Food and Chemical Toxicology. (SCI). 2008; 46: 3401-3406.

27. Lin CC, Yin MC. Anti-glycative and anti-VEGF effects of s-ethyl cysteine and s-propyl cysteine in kidney of diabetic mice. Molecular Nutrition & Food Research (SCI). 2008; 52: 1358-1364.

28. Lin CC, Yin MC. Effect of cysteine-containing compounds on biosynthesis of triacylglycerol and cholesterol and anti-oxidative protection in liver from mice consuming a high-fat diet. British Journal Nutrition. 2008; 99:37-43. (SCI)

29. Tsai MC, Lin CC, Lin CP, Chen TH, Chen TY, Lai DL . Endoscopic treatment of acute lower gastrointestinal bleeding caused by a sigmoid inflammatory fibroid polyp: report of a case. Gastroenterological Journal of Taiwan. 2008; 25: 195-198.

30. Lin CC, Yin MC. Vitamins B depletion, lower iron status and decreased antioxidative defense in patients with chronic hepatitis C treated by pegylated interferon alfa and ribavirin. Clinical Nutrition. 2009; 28: 34-38. (SCI)

31. Yin MC, Lin CC, Wu HC, Tsao SM, Hsu CK. Apoptotic effects of protocatechuic acid in human breast, lung, liver, cervix, and prostate cancer cells: potential mechanisms of action. Journal of Agricultural and Food Chemistry. 2009 Jul 22;57(14):6468-6473(SCI)

32. Yao CC, Huang SM, Lin CC, Ho LC, Chang SW, Chen HM, Cheng YW, Han CP. Assessment of common bile duct using laparoscopic ultrasound during laparoscopic cholecystectomy. Surg Laparosc Endosc Percutan Tech. 2009 Aug;19(4):317-320

33. Chang MH, Tsai MC, Chen TH, Lin WL, Chen TY, Lin CC*. Pneumatosis Cystoides Coli Diagnosed by Endoscopy: Report of a Case. Gastroenterological Journal of Taiwan. 2009; 26;309 -312 (correspondence author)

34. Tsai MC, Chen TH, Lin CC*. Gallbladder perforation with formation of hepatic subcapsular biloma treated by endoscopic naso-biliary drainage. Endoscopy. 2010;42 Suppl 2:E206-207. Epub 2010 Sep 15.(SCI) (correspondence author)

35. Chen TH, Tsai MC, Chang MH, Chen TY, Lin CC*. Lower Gastrointestinal Bleeding from Acute Hemorrhagic Rectal Ulcer in Critically Ill Patients. Gastroenterological Journal of Taiwan.2010;27(3):268-273 (correspondence author)

36. Liu WH, Lin CC, Wang ZH, Mong MC, Yin MC. Effects of protocatechuic acid on trans fat induced hepatic steatosis in mice. Journal of Agricultural and Food Chemistry. 2010 Sep 22;58(18):10247-10252. (SCI) (co- first author)

37. Chang CC, Lin CC*, Chen TY, Chen TH, Tsai MC, Yeo KF, Lin CB, Chang MH. The Analysis of Different Course of Treatment with Pegylated Interferon plus Ribavirin for Genotype 1 Hepatitis C Virus. Chung Shan Medical Journal. 2010; 21;381 -396 (correspondence author)

38. Lai HW, Chen TY, Tsai MC, Chen TH, Tseng SW, Tsai CH, Lin CC*. Cholangiocarcinoma with direct stomach invasion: report of a case. Gastroenterological Journal of Taiwan. 2010, 27, 4, 444-448. (correspondence author)

39. Chen TH, Chen TY, Tsai MC, Hsu JD, Lin CC*. An unusual endoscopic finding of gastric adenocarcinoma. Gastrointestinal Endoscopy.2011;74:1145-1146 (case report).(SCI) (correspondence author)

40. Lin CC, Liu WH, Wang ZH, Yin MC. Vitamins B status and antioxidative defense in patients with chronic hepatitis B or hepatitis C virus infection. European Journal of Nutrition. 2011;50:499-506. (SCI)

41. Lin CC, Huang CY, Mong MC, Chan CY, Yin MC. Antiangiogenic Potential of Three Triterpenic Acids in Human Liver Cancer Cells. Journal of Agricultural and Food Chemistry. 2011;59: 755–762. (SCI)

42. Chen TM, Lin CC*, Huang PT, Wen CF. Metformin associated with lower mortality in diabetic patients with early stage hepatocellular carcinoma after radiofrequency ablation. Journal of Gastroenterology & Hepatology. 2011 May;26(5):858-865. (correspondence author)

43. Lee CY, Lin CC*, Shih HC, Chang CC.The Efficacies of Lamivudine in Chronic Hepatitis B Patients with Acute Flare and Decompensated Liver Function. Chung Shan Medical Journal. 2011; 22: 195-203. (correspondence author)

44. Lai HW, Lin CC*, Tsai MC, Chen TH, Tseng SW, Chang H, Chen TY. Extranodal marginal zone B-cell Lymphoma of the gastrointestinal tract sparing only the esophagus: a case report. The Turkish Journal of Gastroenterology. 2012;23(1):58-62. (SCI) (correspondence author)

45. Liao FT, Hsu LS, Ko JL, Lin CC, Sheu GT. Multiple genomic sequences of hepatitis delta virus are associated with cDNA promoter activity and RNA double rolling-circle replication. Journal of General Virology.2012;93:577-587.

46. Chen TM, Lin CC*, Huang PT, Wen CF. Neutrophil-to-lymphocyte ratio associated with mortality in early hepatocellular carcinoma patients after radiofrequency ablation. Journal of Gastroenterology & Hepatology.2012;27(3);553-561. (correspondence author)

47. Lai HW, Chang CC, Chen TH, Tsai MC, Chen TY, Lin CC*. Safety and efficacy of adefovir therapy for lamivudine-resistant hepatitis B virus infection in renal transplant recipients. Journal of the Formosan Medical Association.2012;111;439-444.(SCI) (correspondence author)

48. Lee CY, Huang KH, Lin CC, Tsai TH, Shih HC.A Neutral Risk on the Development of New-Onset Diabetes Mellitus (NODM) in Taiwanese Patients with Dyslipidaemia Treated with Fibrates.The Scientific World Journal 2012:392734. Epub 2012 Jul 31.

49. Lin CB, Lin CC, Tsay GJ.6-Gingerol Inhibits Growth of Colon Cancer Cell LoVo via Induction of G2/M Arrest. Evidence-based Complementary and Alternative Medicine. 2012; 2012: 326096.(SCI)

50. Chen TM, Chang CC, Huang PT, Wen CF, Lin CC*.Performance of risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B) score in classifying treatment eligibility under 2012 Asian Pacific Association for the Study of the Liver (APASL) guideline for chronic hepatitis B patients. ALIMENTARY PHARMACOLOGY & THERAPEUTICS. 2013;37:243-251. (correspondence author)

51. Tsai CH, Tsai MC, Lin CC*.Unusual Cause of Abdominal Pain After Laparoscopic Cholecystectomy. Gastroenterology. 2013;144:e8-e9. (case report)(SCI) (correspondence author)

52. Chen TH, Chang SW, Huang CC, Wang KL, Yeh KT, Liu CN, Lee H, Lin CC, Cheng YW. The prognostic significance of APC gene mutation and miR-21 expression in advanced stage colorectal cancer.Colorectal Disease. 2013;15(11):1367-1374.

53. Chen FP, Lin CC, Chen TH, Tsai MC, Huang YC.Higher plasma homocysteine is associated with increased risk of developing colorectal polyps. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL . 2013 Feb;65(2):195-201.

54. Lee CY, Jan MS, Yu MC, Lin CC, Wei JC, Shih HC.Relationship between adiponectin and leptin, and blood lipids in hyperlipidemia patients treated with red yeast rice. FORSCHENDE KOMPLEMENTARMEDIZIN. 2013;20(3):197-203. (SCI)

55. Huang KC, Tsai MC, Lin CC*.A Rare Cause of Gastrointestinal Bleeding in a Young Man. Gastroenterology. 2013;145(4): e11-e12.(case report)(SCI) (correspondence author)

56. Wang CC, Chang MH, Lin CC*. A Rare Cause of Gastrointestinal Bleeding. Gastroenterology. 2013;145( 3): e1-e2. (case report)(SCI) (correspondence author)

57. Chen YC, Tsai MC, Chen TY, Lin CC*.Esophageal Bezoar In a Patient with Esophageal Epiphrenic Diverticulum. Endoscopy. 2013; 45(S 02): E193-E194. (case report)(SCI) (correspondence author)

58. Lee CY, Yu MC, Lin CC, Lee MY, Wei JC, Shih HC.Efficacy and safety of herbal medicine yun-cai tea in the treatment of hyperlipidemia: A double-blind placebo-controlled clinical trial. Chinese Journal of Integrative Medicine. 2015 Aug;21(8):587-593.

59. Tsai MC, Chen TH, Lai HW, Chen TY, Chang MH, Lin CC*.Analgesic effect of premedication with meperidine in patients undergoing colonoscopy without sedation. Advances in Digestive Medicine.2014;1:9-13. (SCI)(correspondence author)

60. Chen KM, Chang MH, Lin CC*.A Duodenal Tumor With Intermittent Obstruction.Gastroenterology. 2014 Apr;146(4):e7-8. (case report)(SCI) (correspondence author)

61. Chien RN, Peng CY, Kao JH, Hu TH, Lin CC, Hu CT, Chen CY, Hsieh TY, Lin HC, Chuang WL; Taiwan NA-Registry Group.Higher adherence with 3-year entecavir treatment than lamivudine or telbivudine in treatment-naïve Taiwanese patients with chronic hepatitis B. Journal of Gastroenterology and Hepatology. 2014 Jan;29(1):185-192. (SCI)

62. Chang MH, Chou JW, Chen SM, Tsai MC, Sun YS,Lin CC, Lin CP. Faecal calprotectin as a novel biomarker for differentiating between inflammatory bowel disease and irritable bowel syndrome. Molecular Medicine Reports. 2014 Jul;10(1):522-526. (SCI)

63. Yan SL, Yang HT, Lee YJ, Lin CC, Chang MH, Yin MC. Asiatic Acid ameliorates hepatic lipid accumulation and insulin resistance in mice consuming a high-fat diet.Journal of Agricultural and Food Chemistry. 2014 May 21;62(20):4625-4631. (SCI)

64. Wu HC, Chang CJ, Lin CC, Tsai MC, Chang CC, Tseng MH.Developing Screening Services for Colorectal Cancer on Android Smartphones. Telemedicine and e-Health. 2014 Aug;20(8):687-95. (SCI)

65. Chen FP, Wang HM, Chiang FF, Lin CC, Huang SC, Huang YC. The Metabolic Syndrome Is Associated with an Increased Risk of Colorectal Polyps Independent of Plasma Homocysteine. Annals of Nutrition and Metabolism. 2014 Jun 25;64(2):106-112. (SCI)

66. Chang SC, Yang SS, Chang CC, Lin CC, Chung YC, Li TC.Assessment of health-related quality of life in antiviral-treated Taiwanese chronic hepatitis C patients using SF-36 and CLDQ. Health and Quality of Life Outcomes. 2014 Jun 18;12:97. (SCI)

67. Sheu BS, Wu CY, Wu MS, Chiu CT, Lin CC, Hsu PI, Cheng HC, Lee TY, Wang HP, Lin JT. Consensus on control of risky nonvariceal upper gastrointestinal bleeding in Taiwan with National Health Insurance. BioMed Research International. 2014;2014:563707. doi: 10.1155/2014/563707. Epub 2014 Aug 14.

68. Chang CC, Lin CC, Hsieh WL, Lai HW, Tsai CH, Cheng YW. MicroRNA expression profiling in PBMCs: a potential diagnostic biomarker of chronic hepatitis C.Disease Markers.2014;2014:367157.

69. Yang TW, Wang CC, Lin CC.A symptomatic anorectal polyp.Gastroenterology. 2015 Feb;148(2):298-299. (case report)(SCI) (correspondence author)

70. Weng MT, Wei SC, Lin CC, Tsang YM, Shun CT, Wang JY, Shieh MJ, Wang CY, Wong JM. Seminar Report From the 2014 Taiwan Society of Inflammatory Bowel Disease (TSIBD) Spring Forum (May 24th, 2014): Crohn's Disease Versus Intestinal Tuberculosis Infection. Intestinal Research.2015 Jan;13(1):6-10.Review.

71. Chen HY, Lin CC, Chen TH.A Rare Case of Gastric Ulcerative Mass. Gastroenterology. 2015 . Nov;149(6):e6-7.

72. Chen TM, Lin CC, Huang PT, Wen CF.High post-treatment absolute monocyte count predicted hepatocellular carcinoma risk in HCV patients who failed peginterferon/ribavirin therapy. Tumour Biol. 2016 Jun;37(6):7129-7137.

73. Lee CY, Shih HC, Yu MC, Lee MY, Chang YL, Lai YY, Lee YC, Kuan YH, Lin CC. Evaluation of the potential inhibitory activity of a combination of L. acidophilus, L. rhamnosus and L. sporogenes on Helicobacter pylori: A randomized double-blind placebo-controlled clinical trial.Chin J Integr Med. 2017 Mar;23(3):176-182.

74. Su TH, Hu TH, Chen CY, Huang YH, Chuang WL, Lin CC, Wang CC, Su WW, Chen MY, Peng CY, Chien RN, Huang YW, Wang HY, Lin CL, Yang SS, Chen TM, Mo LR, Hsu SJ, Tseng KC, Hsieh TY, Suk FM, Hu CT, Bair MJ, Liang CC, Lei YC, Tseng TC, Chen CL, Kao JH; C-TEAM study group and the Taiwan Liver Diseases Consortium. Four-year entecavir therapy reduces hepatocellular carcinoma, cirrhotic events and mortality in chronic hepatitis B patients.Liver Int. 2016 Dec;36(12):1755-1764.

75. Lee CY, Yu MC, Perng WT, Lin CC, Lee MY, Chang YL, Lai YY, Lee YC, Kuan YH, Wei JC, Shih HC.No additional cholesterol-lowering effect observed in the combined treatment of red yeast rice and Lactobacillus casei in hyperlipidemic patients: A double-blind randomized controlled clinical trial.Chin J Integr Med. 2017 Aug;23(8):581-588.

76. Chiou GY, Yang TW, Huang CC, Tang CY, Yen JY, Tsai MC, Chen HY, Fadhilah N, Lin CC, Jong YJ. Musashi-1 promotes a cancer stem cell lineage and chemoresistance in colorectal cancer cells.Sci Rep. 2017 May 19;7(1):2172.

77. Wang CC, Tsai MC, Peng CM, Lee HL, Chen HY, Yang TW, Sung WW, Lin CC.Favorable liver cancer mortality-to-incidence ratios of countries with high health expenditure.Eur J Gastroenterol Hepatol. 2017 Dec;29(12):1397-1401.

78. Tsai MC, Wang CC, Lee HL, Peng CM, Yang TW, Chen HY, Sung WW, Lin CC.Health disparities are associated with gastric cancer mortality-to-incidence ratios in 57 countries.World J Gastroenterol. 2017 Nov 28;23(44):7881-7887.

79. Chang CC, Lin CC, Wang CH, Huang CC, Ke TW, Wei PL, Yeh KT, Hsu KC, Hsu NY, Cheng YW. miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation. Oncol Lett. 2018 May;15(5):8107-8117.

80. Lee HL, Peng CM, Huang CY, Wu SY, Tsai MC, Wang CC, Chen SL, Lin CC, Huang CN, Sung WW.Is mortality-to-incidence ratio associated with health disparity in pancreatic cancer? A cross-sectional database analysis of 57 countries.BMJ Open. 2018 Jul 6;8(7):e020618.

81. Tsai MC, Yang TW, Wang CC, Wang YT, Sung WW, Tseng MH, Lin CC*.Favorable clinical outcome of nonalcoholic liver cirrhosis patients with coronary artery disease: A population-based study. World J Gastroenterol. 2018 Aug 21;24(31):3547-3555.

82. Tsai MC, Wang CC, Wang YT, Yang TW, Chen HY, Tseng MH, Lin CC.Major bleeding risk of endoscopic sphincterotomy versus endoscopic papillary balloon dilatation in hemodialysis patients.Saudi J Gastroenterol. 2019 Mar-Apr;25(2):106-112.

83. Lai HW, Wei JC, Hung HC, Lin CC*.Impact of treatment modality on clinical outcome in metastatic colorectal cancer patients stratified by metastatic sites. Postgrad Med. 2019 Mar;131(2):163-170.

84. Wang CC, Tsai MC, Wang YT, Yang TW, Chen HY, Sung WW, Huang SM, Tseng MH, Lin CC. Role of cholecystectomy in choledocholithiasis patients underwent endoscopic retrograde cholangiopancreatography. Sci Rep. 2019; 9:2168. (correspondence author).

85. Wang CC, Tsai MC, Sung WW, Yang TW, Chen HY, Wang YT, Su CC, Tseng MH, Lin CC. Risk of cholangiocarcinoma in patients undergoing therapeutic endoscopic retrograde cholangiopancreatography or cholecystectomy: A population based study. World J Gastrointest Oncol. 2019;11(3): 238-249. (correspondence author) .

86. TW Yang, WH Lee, SJ Tu, WC Huang, HM Chen, TH Sun, MC Tsai, CC Wang, HY Chen, CC Huang, BH Shiu, TL Yang, HT Huang, YP Chou, CH Chou, YR Huang, YR Sun, C Liang, FM Lin, SY Ho, WL Chen, SF Yang, KC Ueng, HD Huang, CN Huang, YJ Jong, CC Lin*. Enterotype-based Analysis of Gut Microbiota along the Conventional Adenoma-Carcinoma Colorectal Cancer Pathway. Sci Rep. 2019 Jul 29;9(1):10923.

87. Chi-Chih Wang, Ming-Chang Tsai, Shao-Chuan Wang, Cheng-Ming Peng, Hsiang-Lin Lee, Hsuan-Yi Chen, Tzu-Wei Yang, Chun-Che Lin, Wen-Wei Sung. Favorable Gallbladder Cancer Mortality-To-Incidence Ratios of Countries with Good Ranking of World’s Health System and High Expenditures on Health. BMC PUBLIC HEALTH. 2019 Jul 31;19(1):1025..

88. Hsin-Wu Lai, James Cheng-Chung Wei, Hung-Chang Hung, Chun-Che Lin. Tumor sidedness influences prognostic impact of lymph node metastasis in colon cancer patients undergoing curative surgery. Scientific Reports. 2019; 9:19892.

89. Tzu-Wei Yang, Chi-Chih Wang, Ming-Chang Tsai, Yao-Tung Wang, Ming-Hseng Tseng and Chun-Che Lin. Comorbidities and Outcome of Alcoholic and Non-Alcoholic Liver Cirrhosis in Taiwan:A Population-Based Study. Int. J. Environ. Res. Public Health 2020, 17, 2825; doi:10.3390/ijerph1708282.

90. Lai HW, Wei JC, Hung HC, Lin CC.Tumor sidedness influences prognostic impact of lymph node metastasis in colon cancer patients undergoing curative surgery. Sci Rep. 2019 Dec 27;9(1):19892.

91. Yang TW, Wang CC, Tsai MC, Wang YT, Tseng MH, Lin CC.Comorbidities and Outcome of Alcoholic and Non-Alcoholic Liver Cirrhosis in Taiwan: A Population-Based Study. Int J Environ Res Public Health. 2020 Apr 20;17(8):2825.

92. Lin CC, Huang WC, Su CH, Lin WD, Wu WT, Yu B, Hsu YM.Effects of Multi-Strain Probiotics on Immune Responses and Metabolic Balance in Helicobacter pylori-Infected Mice. Nutrients. 2020 Aug 17;12(8):2476.

93. Hsu WF, Chuang PH, Chen CK, Wang HW, Tsai MH, Su WP, Chen HY, Yang CY, Lin CC, Huang GT, Lin JT, Lai HC, Peng CY.Predictors of response and survival in patients with unresectable hepatocellular carcinoma treated with nivolumab: real-world experience. Am J Cancer Res. 2020 Dec 1;10(12):4547-4560. eCollection 2020.

94. Wang CC, Tseng MH, Wu SW, Yang TW, Chen HY, Sung WW, Su CC, Wang YT, Lin CC, Tsai MC.Cholecystectomy reduces subsequent cholangiocarcinoma risk in choledocholithiasis patients undergoing endoscopic intervention. World J Gastrointest Oncol. 2020 Dec 15;12(12):1381-1393.

95. Wang CC, Tseng MH, Wu SW, Yang TW, Sung WW, Wang YT, Lee HL, Shiu BH, Lin CC, Tsai MC. The Role of Series Cholecystectomy in High Risk Acute Cholecystitis Patients Who Underwent Gallbladder Drainage. Front Surg. 2021 Feb 15;8:630916. doi: 10.3389/fsurg.2021.630916. eCollection 2021.

96. Wang CC, Tseng MH, Wu SW, Yang TW, Chen HY, Sung WW, Su CC, Wang YT, Chen WL, Lai HC, Lin CC, Tsai MC.Symptomatic cholelithiasis patients have an increased risk of pancreatic cancer: A population-based study. J Gastroenterol Hepatol. 2021 May;36(5):1187-1196. doi: 10.1111/jgh.15234. Epub 2020 Sep 22.

97. Wang HW, Chuang PH, Su WP, Kao JT, Hsu WF, Lin CC, Huang GT, Lin JT, Lai HC, Peng CY. On-Treatment Albumin-Bilirubin Grade: Predictor of Response and Outcome of Sorafenib-Regorafenib Sequential Therapy in Patients with Unresectable Hepatocellular Carcinoma. Cancers (Basel). 2021 Jul 26;13(15):3758. doi: 10.3390/cancers13153758.

98. Lin CC, Yang YC, Chen CY, Yin MC.Combination of s-methyl cysteine and protocatechuic acid provided greater lipid-lowering and anti-inflammatory effects in mice liver against chronic alcohol consumption.Iran J Basic Med Sci. 2021 Aug;24(8):1146-1152.

99. Cheng PN, Chen CY, Yu ML, Lin CC, Lin CY, Peng CY, Tseng KC, Lo CC, Tseng IH, Liu CJ.Elbasvir/grazoprevir is effective and tolerable for the treatment of HCV GT1-infected patients: A real world multicenter observatory study in Taiwan. J Microbiol Immunol Infect. 2021 Aug;54(4):588-595. doi: 10.1016/j.jmii.2020.05.004. Epub 2020 May 22

100. Hsu WF, Wang HW, Chen CK, Lai HC, Chuang PH, Tsai MH, Su WP, Chen HY, Chu CS, Chou JW, Chen SH, Tsai TY, Hsiao WD, Lin CC, Huang GT, Lin JT, Peng CY.Alpha-fetoprotein response predicts treatment outcomes in patients with unresectable hepatocellular carcinoma receiving immune checkpoint inhibitors with or without tyrosine kinase inhibitors or locoregional therapies. Am J Cancer Res. 2021 Dec 15;11(12):6173-6187. eCollection 2021.

101. Chu CS, Yang CY, Yeh CC, Lin RT, Chen CC, Bai LY, Hung MC, Lin CC, Wu CY, Lin JT.Endoscopic ultrasound-guided fine-needle biopsy as a tool for studying the intra-tumoral microbiome in pancreatic ductal adenocarcinoma: a pilot study. Sci Rep. 2022 Jan 7;12(1):107.

102. Hsu WF, Chang CY, Chang CC, Chang LC, Chen CH, Lin CC, Lin YM, Lee CL, Wu HY, Lee HC, Lee YC, Su MY, Lin LJ, Chia SL, Wu MS, Chiu HM. Risk of colonoscopy-related complications in a fecal immunochemical test-based population colorectal cancer screening program. Colonoscopy Quality Assurance Joint Working Group of Taiwan Colorectal Cancer Screening Program and Digestive Endoscopy Society of Taiwan.Endoscopy. 2022 Mar;54(3):290-298. doi: 10.1055/a-1328-5126. Epub 2021 Feb 24.

103. Lin RT, Chen PL, Yang CY, Yeh CC, Lin CC, Huang WH, Chung AK, Lin JT. Risk factors related to age at diagnosis of pancreatic cancer: a retrospective cohort pilot study.

BMC Gastroenterol. 2022 May 14;22(1):243.

104. Yang TW, Wang CC, Sung WW, Ting WC, Lin CC, Tsai MC.The effect of coffee/caffeine on postoperative ileus following elective colorectal surgery: a meta-analysis of randomized controlled trials. Int J Colorectal Dis. 2022 Mar;37(3):623-630. doi: 10.1007/s00384-021-04086-3. Epub 2022 Jan 6.

105. Yen YA, Wang CC, Sung WW, Fang KC, Huang SM, Lin CC, Tsai MC, Yang TW. Intragastric injection of botulinum toxin A for weight loss: A systematic review and meta-analysis of randomized controlled trials. J Gastroenterol Hepatol. 2022 Jun;37(6):983-992. doi: 10.1111/jgh.15847. Epub 2022 Apr 22.

106. Lin CI, Chen ZC, Chen CH, Chang YH, Lee TC, Tang TT, Yu TW, Yang CM, Tsai MC, Huang CC, Yang TW, Lin CC, Wang RH, Chiou GY, Jong YJ, Chao JI. Co-inhibition of Aurora A and Haspin kinases enhances survivin blockage and p53 induction for mitotic catastrophe and apoptosis in human colorectal cancer.Biochem Pharmacol. 2022 Dec;206:115289. doi: 10.1016/j.bcp.2022.115289. Epub 2022 Oct 12.

107. Lai HW, Hung HC, Lin CC. Impact of hepatitis virus infection on inpatient outcomes of acute pancreatitis: A population-based study. Medicine (Baltimore). 2023 Jun 2;102(22):e33952.

108. Chien TL, Wu YC, Lee HL, Sung WW, Yu CY, Chang YC, Lin CC, Wang CC, Tsai MC.PNU-74654 Induces Cell Cycle Arrest and Inhibits EMT Progression in Pancreatic Cancer. Medicina (Kaunas). 2023 Aug 24;59(9):1531. doi: 10.3390/medicina59091531.

109. Tsai MC, Yen HH, Tsai HY, Huang YK, Luo YS, Kornelius E, Sung WW, Lin CC, Tseng MH, Wang CC. Artificial intelligence system for the detection of Barrett's esophagus. World J Gastroenterol. 2023 Dec 28;29(48):6198-6207. doi: 10.3748/wjg.v29.i48.6198.

110. Wang CC, Huang JY, Weng LH, Hsu YC, Sung WW, Huang CY, Lin CC, Wei JC, Tsai MC. Association between Cholecystectomy and the Incidence of Pancreaticobiliary Cancer after Endoscopic Choledocholithiasis Management. Cancers (Basel). 2024 Feb 28;16(5):977. doi: 10.3390/cancers16050977.